Chorea is a kind of movement disorders result from many conditions. Hyperglycemic hemichoreais a one of them which can be seen patients with type 2 diabetes in long-term poor glycemic control. In this case, we reported a 58-year-old woman who presented with involuntary movements of left limbs. Her MRI can see hyper intensity in T1. After hypoglycemic therapy, she symptom of hemichorea got reverse to some extent. This case is relatively rare in clinic. We reviewed the clinical cases and discussed the possible mechanism.