To understand the physical health of women during pregnancy in Beijing, the data of pregnant women who attended the obstetrics outpatient clinic of Miyun District Maternal and Child Health Hospital of Beijing from 2017 to 2020 were selected. The blood lipid indexes (the triglyceride (TG), total cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C)), 75g oral glucose tolerance test (fasting plasma glucose, 1hplasma glucose, 2h plasma glucose) and thyroid hormones (thyroid stimulating hormone (TSH), free thyroxine (FT4), free triiodothyronine (FT3), total thyroxine (TT4), and total triiodothyronine (TT3)) of 11 parameters were analyzed. The levels of lipid and thyroid hormones in pregnant women, during 2017-2021, showed a general trend of decreasing and then reversing increase, and the difference was statistically significant (P< 0.0001). Fasting blood glucose, 1h postprandial and 2h postprandial blood glucose showed a trend of chronological increase (P< 0.0001). Except LDL-C, Lipid index levels and fasting glucose, 1h postprandial and 2h postprandial glucose levels increased with age in pregnant women (P< 0.0001). The opposite trend was observed for the indicators of thyroid function measurement. There were chronological differences in the abnormal rates of lipid index, OGTT, and thyroid hormones during pregnancy, but the trend was not significant. The abnormal rates of HDL-C, LDL-C were high. Lipid, blood glucose and thyroid hormone index in Miyun District of Beijing can better reflect the physical condition of pregnant women, and strengthening the indexes is of great value for eugenics and expected female health.