This paper illustrates that the brain is a biophysical entity in which both sensory and biological input sustain its biophysical and computational function. This leads to the conclusion that the brain works in a multi-level and coherent manner to optimise and/or regulate the body’s multi-systemic stability and function.

It further illustrates that the ‘optimisation of blood glucose levels’ exhibits the characteristics of a neurally regulated physiological system in which blood glucose levels are regulated between higher and lower limits i.e. 4-8 mmol/l blood glucose; that types 1 and 2 diabetes are comorbidities thereby explaining the inaccuracies reported when diagnosing diabetes; that under pathological conditions mainly in the pancreas, but also as a result of pathological onset in adjacent organs and systems, there is an imbalance between insulin expression and insulin reactivity which leads to increased or decreased blood glucose levels, elevated blood viscosity, the onset of free radical reactions, the subsequent production of complex glycated proteins/lipids and metabolites, altered colour perception.

Moreover such precise knowledge; which is embodied in Grakov’s mathematical model of the relationship between sense perception, brain function, the autonomic nervous system and physiological systems, and pathological onset; can be applied to screen the patient’s health (as Strannik Virtual Scanning) and/or as a neuro modulation type technique (as Strannik Light Therapy) to treat autonomic dysfunction and the range of comorbidities experienced by diabetic and obese patients.