Journal of Pediatrics & Child Care

Case Report

Neonatal Macrocytic Anemia Following in Utero Exposure to Triumeq (Abacavir/Dolutegravir/Lamivudine): A Case Report

Pan M1 and Jain SK2*

1John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX, USA
2Department of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA
*Address for Correspondence:Sunil K. Jain, Department of Pediatrics, University of Texas Medical Branch, Galveston, TX, USA E-mail Id: skjain@utmb.edu
Submission: 19 December, 2024 Accepted: 26 February, 2025 Published: 04 March, 2025
Copyright: © 2025 Pan M, et al. This is an open access article distributed under the Creative Commons Attr-ibution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We report a case of neonatal macrocytic anemia in dizygotic twins born to an HIV-positive mother treated with Triumeq during pregnancy. Despite achieving an undetectable maternal viral load, both twins required NICU care for metabolic acidosis and respiratory distress and developed severe anemia necessitating transfusions. This is the first documented case of fetal and neonatal macrocytic anemia associated with Triumeq, highlighting the need for awareness of potential hematologic side effects of antiretroviral therapy (ART) in pregnancy.