Toxic epidermal necrolysis (TEN) is a rare, life threatening, severe mucocutaneous adverse reaction characterised by extensive epidermal detachment, erosion of mucosae and severe constitutional symptoms [1]. Worldwide, the incidence of TEN is estimated to be between 1-2 per million people per year and in India 0.4 to 1.2 cases per million people per year [2-5]. The mortality rate of TEN is about 20 to 60 percent [6,7]. Severe sepsis is an important complication and main cause of death in TEN. The prognosis is improved by supportive care especially with specialist nurses to achieve favourable outcomes for patients [8].

Nursing care in TEN is paramount, as management focuses on wound healing, infection prevention, hydration, nutrition, psychological support and the prevention of long-term complications. Nurses, skilled in infection prevention and barrier nursing are in an ideal position to manage patients with TEN to achieve good outcome despite their challenging disease course [9].