Background: Kimura’s disease is a rare idiopathic inflammatory disease of unknown etiology, often involving head and neck lymph nodes. Because the clinical manifestations are not typical, the diagnosis is difficult or it is misdiagnosed as malignant tumor. After the diagnosis of Kimura’s disease, due to the high recurrence rate, surgery, drugs, radiation and other comprehensive treatment methods are often used. Here we present a rare case of forehead Kimura’s disease from diagnosis to Iodine-125 implantation without recurrence.
Case Report: A 58-year-old man was diagnosed with Kimura’s disease and underwent 1 excision biopsy, 3 surgical excisions, and 2 postoperative recurrences. Since the patient refused to take oral immunosuppressants for a long period of time and local radiotherapy for several times, after the patient’s second recurrence resection, we used a gun implant to retrograde implant 125 iodide particles in the subcutaneous area of the forehead under local anesthesia with the consent of the patient, and implanted a total of 4 Iodine-125 particles at a interval of 1cm.After 1 year of implantation, the patient’s forehead mass showed no obvious protrusion and pruritus. After 1 year and 6 months of implantation, the patient’s forehead mass showed no obvious protrusion and pruritus, and the patient indicated satisfactory results.
Conclusion:When it is difficult to confirm the diagnosis of forehead skin masses with similar clinical manifestations as this patient, the possibility of Kimura’s disease should be considered, and comprehensive treatment such as surgery and adjuvant radiotherapy should be actively taken according to the pathological situation. Iodine-125 particle implantation may provide a new approach for the comprehensive treatment of Kimura’s disease patients to reduce postoperative recurrence. More clinical controlled studies are needed to confirm these findings in the context of radiation safety studies.