Journal of Orthopedics & Rheumatology

Research Article

Prevalence of Metabolic Syndrome in Patients with Ankylosing Spondylitis

El Hassani Sbai S*, Rostom S, Amine B and Bahiri R

Department of Rheumatology A (Pr R. Bahiri), University Hospital of Rabat-Sale, Morocco
*Address for Correspondence: El Hassani Sbai S, Department of Rheumatology A (Pr R Bahiri), El Ayachi Hospital, 11000, Sale, Morocco, Tel: 00-212-537-78-29-19 / 17-14 Fax: 00- 212-537-88-33-27; E-mail: elhassanisalma1@gmail.com
Submission: 13 November 2019; Accepted: 18 December 2019; Published: 20 December 2019
Copyright: © 2019 El Hassani Sbai S, et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background: The aim of our study was to assess the prevalence of metabolic syndrome in ankylosing spondylitis (As) and identify factors that are associated with its presence.
Methods: A cross-sectional study including AS patients fulfilling the modified 1984 New York criteria for AS criteria, and age- and sexmatched controls.
MetS prevalence was assessed, using six MetS definitions (Joint Consensus, National Cholesterol Education Program 2004 and 2001, International Diabetes Federation, World Health Organization and European Group for Study of Insulin Resistance). Physical activity was assessed by the IPAQ (international physical activity questionnaire) short version. Quality of life was assessed by the SF-36 (Short Form 36).
Results: One hundred and ten AS patients were included with 68% male and median age 36 years [23-44]. The control group consisted of 100 healthy control subjects with 67% male and median age 35 years [21-44]. MetS prevalence rates varied from 8.2% to 13.6% in AS according to the definition used, when it was between 1 to 5% in the control group( p=0,01). In multivariate analysis only persists a significant association between MetS and patients ages (OR=1.12; IC [1.04-1.21]; p=0.003).
Conclusion: In this study, the frequency of MetS was observed to be higher in patients with AS than the controls for every definition of MetS. The occurrence of metabolic syndrome appears to be related to age regardless to the activity, severity and treatment of AS.